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Invitrogen™ UBE2A/UBE2B Polyclonal Antibody
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Catalog No. PIPA5104442
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100 μL
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PIPA5104442 100 μL
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Catalog No. PIPA5104442 Supplier Invitrogen™ Supplier No. PA5104442
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total UBE2A/B.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2A/UBE2B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Ube2a
Gene Accession No. P49459, P63146, P63147, P63149, Q9Z255
Gene Alias 2610301N02Rik; E2 protein; E2 ubiquitin-conjugating enzyme A; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; E2-14k; E2-17kDa; HHR6A; HHR6B; HR6A; HR6B; Mhr6a; mHR6B; mp:zf637-2-000771; MRXS30; MRXSN; RAD6 homolog A; RAD6 homolog B; Rad6a; RAD6B; si:bz46j2.4; UBC2; Ube2a; Ube2b; Ubiquitin carrier protein A; ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2 A; ubiquitin conjugating enzyme E2 B; ubiquitin conjugating enzyme E2A; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme; ubiquitin-conjugating enzyme E2 A; Ubiquitin-conjugating enzyme E2 B; ubiquitin-conjugating enzyme E2(14k); Ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); ubiquitin-conjugating enzyme E2A, RAD6 homolog; ubiquitin-conjugating enzyme E2B; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-conjugating enzyme HR6A; ubiquitin-protein ligase A; Ubiquitin-protein ligase B; wu:fa01h11; zgc:100921
Gene Symbols Ube2a, Ube2b
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBE2B(Accession P63146), corresponding to amino acid residues N94-I144.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22209, 22210, 298317, 7319, 7320, 81816
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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