Invitrogen™ UBE2A/UBE2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104442

Catalog No. PIPA5104442

Description

Antibody detects endogenous levels of total UBE2A/B.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Specifications

• Antigen: UBE2A/UBE2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ube2a
• Gene Alias: 2610301N02Rik; E2 protein; E2 ubiquitin-conjugating enzyme A; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; E2-14k; E2-17kDa; HHR6A; HHR6B; HR6A; HR6B; Mhr6a; mHR6B; mp:zf637-2-000771; MRXS30; MRXSN; RAD6 homolog A; RAD6 homolog B; Rad6a; RAD6B; si:bz46j2.4; UBC2; Ube2a; Ube2b; Ubiquitin carrier protein A; ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2 A; ubiquitin conjugating enzyme E2 B; ubiquitin conjugating enzyme E2A; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme; ubiquitin-conjugating enzyme E2 A; Ubiquitin-conjugating enzyme E2 B; ubiquitin-conjugating enzyme E2(14k); Ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); ubiquitin-conjugating enzyme E2A, RAD6 homolog; ubiquitin-conjugating enzyme E2B; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-conjugating enzyme HR6A; ubiquitin-protein ligase A; Ubiquitin-protein ligase B; wu:fa01h11; zgc:100921
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22209, 22210, 298317, 7319, 7320, 81816
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P49459, P63146, P63147, P63149, Q9Z255
• Gene Symbols: Ube2a, Ube2b
• Immunogen: A synthesized peptide derived from human UBE2B(Accession P63146), corresponding to amino acid residues N94-I144.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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