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Invitrogen™ UBE2B Polyclonal Antibody
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Catalog No. PIPA530200
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100 μL
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PIPA530200 100 μL
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Catalog No. PIPA530200 Supplier Invitrogen™ Supplier No. PA530200
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: mouse brain, DDDDK-tagged UBE2B-transfected 293T. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (95%), Xenopus laevis (98%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2B
Applications Western Blot
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene Ube2b
Gene Accession No. P63146, P63147
Gene Alias 2610301N02Rik; E2 protein; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; E2-14k; E2-17kDa; HHR6B; HR6B; mHR6B; RAD6 homolog B; Rad6b; UBC2; Ube2b; Ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2 B; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2(14k); ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-protein ligase B
Gene Symbols Ube2b
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human UBE2B. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22210, 7320
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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