Invitrogen™ UBE2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110674

Catalog No. PIPA5110674

Description

Immunogen sequence: LMRDFKRLQE DPPVGVSGAP SENNIMQWNA VIFGPEGTPF EDGTFKLVIE FSEEYPNKPP TVRFLSKMFH PNVYADGSIC LDILQNRWSP TYDVSSILTS IQSLLDEPNP NSPANSQAAQ.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Specifications

• Antigen: UBE2B
• Classification: Polyclonal
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P63146
• Gene Symbols: Ube2b
• Immunogen: Recombinant Protein corresonding to Human UBE2B. Recombinant protein control fragment (Product #RP-105607).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry
• Conjugate: Unconjugated
• Gene: Ube2b
• Gene Alias: 2610301N02Rik; E2 protein; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; E2-14k; E2-17kDa; HHR6B; HR6B; mHR6B; RAD6 homolog B; Rad6b; UBC2; Ube2b; Ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2 B; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2(14k); ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-protein ligase B
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7320
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov