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Invitrogen™ UBE2B Recombinant Rabbit Monoclonal Antibody (2Z3R2)
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Catalog No. PIMA542600
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100 μL
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PIMA542600 100 μL
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Catalog No. PIMA542600 Supplier Invitrogen™ Supplier No. MA542600
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Description

Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HeLa, 293T, NIH/3T3, K-562, Mouse testis, Mouse heart, Rat testis. The target is usually found in the following locations: Cell membrane, Nucleus. Immunogen sequence: FKLVIEFSEE YPNKPPTVRF LSKMFHPNVY ADGSICLDIL QNRWSPTYDV SSILTSIQSL LDEPNPNSPA NSQAAQLYQE NKREYEKRVS AIVEQSWNDS.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2B
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 2Z3R2
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ube2b
Gene Accession No. P63146, P63147, P63149
Gene Alias 2610301N02Rik; E2 protein; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; E2-14k; E2-17kDa; HHR6B; HR6B; mHR6B; RAD6 homolog B; Rad6b; UBC2; Ube2b; Ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2 B; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2(14k); ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-protein ligase B
Gene Symbols Ube2b
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22210, 7320, 81816
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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