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Invitrogen™ UBE2B Recombinant Rabbit Monoclonal Antibody (JE56-12)
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Catalog No. PIMA542490
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100 μL
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PIMA542490 100 μL
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Catalog No. PIMA542490 Supplier Invitrogen™ Supplier No. MA542490
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: A431 cell lysate, THP-1 cell lysate, HepG2 cell lysate, zebrafish tissue lysates, human breast carcinoma tissue, human fetal skeletal muscle tissue. Subcellular Location: Nucleus, Cell membrane.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2B is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE56-12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Ube2b
Gene Accession No. P63146
Gene Alias 2610301N02Rik; E2 protein; E2 ubiquitin-conjugating enzyme B; E2(14k); E214K; E2-14k; E2-17kDa; HHR6B; HR6B; mHR6B; RAD6 homolog B; Rad6b; UBC2; Ube2b; Ubiquitin carrier protein B; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2 B; ubiquitin conjugating enzyme E2B; ubiquitin-conjugating enzyme E2 B; Ubiquitin-conjugating enzyme E2(14k); ubiquitin-conjugating enzyme E2-17 kDa; ubiquitin-conjugating enzyme E2B; ubiquitin-conjugating enzyme E2B (RAD6 homolog); ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae); ubiquitin-conjugating enzyme E2B, RAD6 homolog; ubiquitin-conjugating enzyme E2B, RAD6 homology; ubiquitin-protein ligase B
Gene Symbols Ube2b
Host Species Rabbit
Immunogen Synthetic peptide within N-terminal Human Ube2B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 437020, 7320
Target Species Human, Zebrafish
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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