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Invitrogen™ UBE2C Polyclonal Antibody
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Catalog No. PIPA583234
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100 μL
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PIPA583234 100 μL
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Catalog No. PIPA583234 Supplier Invitrogen™ Supplier No. PA583234
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPVGKRLQQE LMTLMMSGDK GISAFPESDN LFKWVGTIHG AAGTVYEDLR YKLSLEFPSG YPYNAPTVKF LTPCYHPNVD Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 100%.

This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2C
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene UBE2C
Gene Accession No. O00762
Gene Alias (E3-independent) E2 ubiquitin-conjugating enzyme C; 1110015A16Rik; cyclin-selective ubiquitin carrier protein; D2Ertd695e; dJ447F3.2; E2 ubiquitin-conjugating enzyme C; mitotic-specific ubiquitin-conjugating enzyme; RP3-447F3.1; ubcH10; UBE2C; Ubiquitin carrier protein C; ubiquitin conjugating enzyme E2 C; ubiquitin conjugating enzyme E2C; ubiquitin-conjugating enzyme E2 C; ubiquitin-conjugating enzyme E2C; ubiquitin-protein ligase C
Gene Symbols UBE2C
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human UBE2C. Recombinant protein control fragment (Product #RP-103205).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11065
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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