UBE2D1 Monoclonal Antibody (OTI1E7), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA803633

Catalog No. 50-167-9857

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Specifications

• Antigen: UBE2D1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P51668
• Gene Symbols: UBE2D1
• Immunogen: Full length human recombit protein of human UBE2D1 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1E7
• Conjugate: Unconjugated
• Gene: UBE2D1
• Gene Alias: E2(17)KB1, SFT, UBC4/5, UBCH5, UBCH5A
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7321
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid