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Invitrogen™ UBE2D1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528959

Catalog No. PIPA528959


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Description

Description

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (95%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UBE2D1
Polyclonal
Unconjugated
UBE2D1
(E3-independent) E2 ubiquitin-conjugating enzyme D1; E2 ubiquitin-conjugating enzyme D1; E2(17)KB 1; E2(17)KB1; SFT; Stimulator of Fe transport; UBC 4/5; UBC4/5; UBC4/5 homolog; UBC5A; UBCH 5; UBCH 5A; UBCH5; UBCH5A; UBE2D1; ubiquitin; Ubiquitin carrier protein D1; ubiquitin conjugating enzyme E2 D1; ubiquitin conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2 D1; Ubiquitin-conjugating enzyme E2(17)KB 1; ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog; ubiquitin-protein ligase D1
Rabbit
Antigen Affinity Chromatography
RUO
216080, 7321
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
P51668, P61080
UBE2D1
Full length human UBE2D1 Recombinant protein.
100 μL
Primary
Human, Mouse
Antibody
IgG
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