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UBE2D1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 113731AP150UL

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Catalog No. 50-172-7103


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Description

Description

This antibody is specific to UBE2D1.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
Specifications

Specifications

UBE2D1
Polyclonal
Unconjugated
UBE2D1
E2(17)KB1, SFT, Stimulator of Fe transport, UBC4/5, UBC4/5 homolog, UBC5A, UBCH5, UBCH5A, UBE2D1, Ubiquitin carrier protein D1, Ubiquitin protein ligase D1
Rabbit
Antigen Affinity Chromatography
RUO
216080, 361831, 7321
-20°C
Liquid
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
D3ZDK2, P51668, P61080
Ube2d1
UBE2D1-Specific Fusion Protein Ag1932
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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