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UBE2D1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988492
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50-198-8492 100 μL
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Catalog No. 50-198-8492 Supplier Bioss Supplier No. BS8356R
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Description

Rabbit Polyclonal Antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.

Specifications

Antigen UBE2D1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene UBE2D1
Gene Accession No. P51668
Gene Alias (E3-independent) E2 ubiquitin-conjugating enzyme D1; E2 ubiquitin-conjugating enzyme D1; E2(17)KB 1; E2(17)KB1; SFT; Stimulator of Fe transport; UBC 4/5; UBC4/5; UBC4/5 homolog; UBC5A; UBCH 5; UBCH 5A; UBCH5; UBCH5A; Ube2d1; ubiquitin; Ubiquitin carrier protein D1; ubiquitin conjugating enzyme E2 D1; ubiquitin conjugating enzyme E2D 1; Ubiquitin-conjugating enzyme E2 D1; Ubiquitin-conjugating enzyme E2(17)KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; ubiquitin-conjugating enzyme E2D 1; ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 1, UBC4/5 homolog; Ubiquitin-protein ligase D1
Gene Symbols UBE2D1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human UBE2D1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7321
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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