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Invitrogen™ UBE2D3 Polyclonal Antibody
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Catalog No. PIPA5100698
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PIPA5100698 100 μL
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Catalog No. PIPA5100698 Supplier Invitrogen™ Supplier No. PA5100698
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total UBE2D3.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2D3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene UBE2D3
Gene Accession No. P61077, P61078, P61079
Gene Alias (E3-independent) E2 ubiquitin-conjugating enzyme D3; 1100001F19Rik; 9430029A22Rik; AA414951; E2 ubiquitin-conjugating enzyme D3; E2(17)KB 3; E2(17)KB3; eff; fb36f02; LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 D3; MGC43926; MGC5416; PAPase; Phosphoarginine phosphatase; PRO2116; similar to phosphoarginine phosphatase; UBC4/5; UBC5C; UBCH5C; Ube2d3; UBE2D3P; Ubiquitin carrier protein D3; ubiquitin conjugating enzyme E2 D3; ubiquitin conjugating enzyme E2D 3; ubiquitin-conjugating enzyme E2 D3; Ubiquitin-conjugating enzyme E2(17)KB 3; ubiquitin-conjugating enzyme E2-17 kDa 3; ubiquitin-conjugating enzyme E2D 2; ubiquitin-conjugating enzyme E2D 3; ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); ubiquitin-protein ligase D3; Unknown (protein for MGC:127427); wu:fb36f02; zgc:56340
Gene Symbols UBE2D3
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBE2D3(Accession P61077), corresponding to amino acid residues S108-M147.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66105, 7323, 81920
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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