Invitrogen™ UBE2E1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542281

Catalog No. PIPA542281

Description

Peptide sequence: PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%.

UBE2E1 catalyzes the covalent attachment of ubiquitin to other proteins. UBE2E1 mediates the selective degradation of short-lived and abnormal proteins.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: UBE2E1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE2E1
• Gene Alias: (E3-independent) E2 ubiquitin-conjugating enzyme E1; E2 ubiquitin-conjugating enzyme E1; Ubce5; UBCH6; ubcM2; UbcM3; UBE2E1; Ubiquitin carrier protein E1; ubiquitin conjugating enzyme E2 E1; ubiquitin conjugating enzyme E2E 1; ubiquitin-conjugating enzyme 5; ubiquitin-conjugating enzyme E2 E1; Ubiquitin-conjugating enzyme E2 E1-like protein; ubiquitin-conjugating enzyme E2E 1; ubiquitin-conjugating enzyme E2E 1 (homologous to yeast UBC4/5); ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2E 1, UBC4/5 homolog; ubiquitin-protein ligase E1; zgc:171646
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7324
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P51965
• Gene Symbols: UBE2E1
• Immunogen: Synthetic peptide directed towards the middle region of human UBE2E1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG