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UBE2K Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
$518.60
Specifications
Antigen | UBE2K |
---|---|
Concentration | 0.33 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-172-7491
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Proteintech Group Inc
118343AP150UL |
150 μL |
Each of 1 for $518.60
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Description
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of ′Lys-48′-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B; in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein-dependent degradation of RB1.Specifications
UBE2K | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
P61086, P61087 | |
289623, 3093, 53323 | |
UBE2K Fusion Protein Ag2415 | |
Primary | |
-20°C | |
UBE2K |
0.33 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
E2-25K, HIP 2, HIP2, HYPG, LIG, UBE2K, Ubiquitin carrier protein, Ubiquitin protein ligase | |
Ube2k | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |
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