Invitrogen™ UBE2L6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542284

Catalog No. PIPA542284

Description

Peptide sequence: LLLPDQPPYH LKAFNLRISF PPEYPFKPPM IKFTTKIYHP NVDENGQICL Sequence homology: Cow: 85%; Dog: 85%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 100%; Rat: 85%; Zebrafish: 85%.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

Specifications

• Antigen: UBE2L6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE2L6
• Gene Alias: 2810489I21Rik; E2 ubiquitin conjugating enzyme; E2 ubiquitin-conjugating enzyme L6; MGC40331; retinoic acid induced gene B protein; retinoic acid-induced gene B protein; RIG-B; Ubce8; UBCH8; Ubcm8; UBE2L6; Ubiquitin carrier protein L6; ubiquitin conjugating enzyme E2 L6; ubiquitin conjugating enzyme E2L 6; Ubiquitin/ISG15-conjugating enzyme E2 L6; ubiquitin-conjugating enzyme 8; ubiquitin-conjugating enzyme E2L 6; Ubiquitin-protein ligase L6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9246
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O14933
• Gene Symbols: UBE2L6
• Immunogen: Synthetic peptide directed towards the N-terminal of human UBE2L6 (aa 38-87).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov