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UBE2T/HSPC150 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
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Catalog No. 501726027 Shop All Proteintech Group Inc Products
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50-172-6027 150 μL
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Catalog No. 50-172-6027 Supplier Proteintech Group Inc Supplier No. 101052AP150UL
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Rabbit Polyclonal Antibody

UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.

Specifications

Antigen UBE2T/HSPC150
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.37 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene UBE2T
Gene Accession No. Q9CQ37, Q9NPD8
Gene Alias HSPC150, PIG50, UBE2T, Ubiquitin carrier protein T, Ubiquitin protein ligase T
Gene Symbols Ube2t
Host Species Rabbit
Immunogen UBE2T/HSPC150 Fusion Protein Ag0153
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29089, 360847, 67196
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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