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Invitrogen™ UBE2T Polyclonal Antibody
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Catalog No. PIPA5101948
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100 μL
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PIPA5101948 100 μL
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Catalog No. PIPA5101948 Supplier Invitrogen™ Supplier No. PA5101948
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total UBE2T.

UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2T
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene UBE2T
Gene Accession No. Q9CQ37, Q9NPD8
Gene Alias 2700084L22Rik; C80607; Cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; FANCT; HSPC150; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50; RGD1310816; Ube2t; Ubiquitin carrier protein T; ubiquitin conjugating enzyme E2 T; ubiquitin conjugating enzyme E2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-protein ligase T
Gene Symbols UBE2T
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBE2T(Accession Q9NPD8), corresponding to amino acid residues T72-D122.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29089, 67196
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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