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UBE2T Polyclonal Antibody, Invitrogen™

Catalog No. PIPA528464
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PIPA528464 100 μL
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Catalog No. PIPA528464 Supplier Thermo Scientific Supplier No. PA528464

Description

Rabbit Polyclonal Antibody

Recommended positive controls: NT2D1, IMR32. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2T
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene UBE2T
Gene Accession No. Q9NPD8
Gene Alias 2700084L22Rik; C80607; Cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; FANCT; HSPC150; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50; RGD1310816; Ube2t; Ubiquitin carrier protein T; ubiquitin conjugating enzyme E2 T; ubiquitin conjugating enzyme E2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-protein ligase T
Gene Symbols UBE2T
Host Species Rabbit
Immunogen Synthetic peptide corresponding to a region within amino acids 135 and 197 of Human UBE2T
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29089
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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