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Invitrogen™ UBE2U Monoclonal Antibody (3D4)
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Catalog No. PIMA523084
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100 μg
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Catalog No. Quantity
PIMA523084 100 μg
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Catalog No. PIMA523084 Supplier Invitrogen™ Supplier No. MA523084
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Description

Mouse Monoclonal Antibody

Peptide Sequence: LHRDFCDLKE NNYKGITAKP VSEDMMEWEV EIEGLQNSVW QGLVFQLTIH FTSEYNYAPP VVKFITIPFH PNVDPHTGQP CIDFLDNPEK WNTN.

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires ATP-dependent activation of the Ub C-terminus and assembly of multi-Ub chains by a Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2U (ubiquitin-conjugating enzyme E2U) is a 321 amino acid E2 ubiquitin conjugating enzyme that catalyzes the covalent attachment of ubiquitin to other proteins. Existing as two alternatively spliced isoforms, UBE2U is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2U
Applications ELISA, Immunocytochemistry
Classification Monoclonal
Clone 3D4
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene UBE2U
Gene Accession No. Q5VVX9
Gene Alias E2 ubiquitin-conjugating enzyme U; MGC35130; RP4-636O23.1; testicular tissue protein Li 216; UBE2U; Ubiquitin carrier protein U; ubiquitin conjugating enzyme E2 U (putative); ubiquitin conjugating enzyme E2U (putative); ubiquitin-conjugating enzyme E2 U; ubiquitin-conjugating enzyme E2U (putative); ubiquitin-protein ligase U
Gene Symbols UBE2U
Host Species Mouse
Immunogen UBE2U (NP_542783, 9 a.a. ~ 102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 148581
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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