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Invitrogen™ UBE2U Polyclonal Antibody
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Catalog No. PIPA576373
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100 μL
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PIPA576373 100 μL
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Catalog No. PIPA576373 Supplier Invitrogen™ Supplier No. PA576373
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires ATP-dependent activation of the Ub C-terminus and assembly of multi-Ub chains by a Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2U (ubiquitin-conjugating enzyme E2U) is a 321 amino acid E2 ubiquitin conjugating enzyme that catalyzes the covalent attachment of ubiquitin to other proteins. Existing as two alternatively spliced isoforms, UBE2U is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2U
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene UBE2U
Gene Accession No. Q5VVX9
Gene Alias E2 ubiquitin-conjugating enzyme U; MGC35130; RP4-636O23.1; testicular tissue protein Li 216; UBE2U; Ubiquitin carrier protein U; ubiquitin conjugating enzyme E2 U (putative); ubiquitin conjugating enzyme E2U (putative); ubiquitin-conjugating enzyme E2 U; ubiquitin-conjugating enzyme E2U (putative); ubiquitin-protein ligase U
Gene Symbols UBE2U
Host Species Rabbit
Immunogen Recombinant fusion protein of human UBE2U.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 148581, 381534
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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