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Invitrogen™ UBE2U Polyclonal Antibody
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Catalog No. PIPA599748
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PIPA599748 100 μL
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Catalog No. PIPA599748 Supplier Invitrogen™ Supplier No. PA599748
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total UBE2U.

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires ATP-dependent activation of the Ub C-terminus and assembly of multi-Ub chains by a Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2U (ubiquitin-conjugating enzyme E2U) is a 321 amino acid E2 ubiquitin conjugating enzyme that catalyzes the covalent attachment of ubiquitin to other proteins. Existing as two alternatively spliced isoforms, UBE2U is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE2U
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene UBE2U
Gene Accession No. Q5VVX9
Gene Alias E2 ubiquitin-conjugating enzyme U; MGC35130; RP4-636O23.1; testicular tissue protein Li 216; UBE2U; Ubiquitin carrier protein U; ubiquitin conjugating enzyme E2 U (putative); ubiquitin conjugating enzyme E2U (putative); ubiquitin-conjugating enzyme E2 U; ubiquitin-conjugating enzyme E2U (putative); ubiquitin-protein ligase U
Gene Symbols UBE2U
Host Species Rabbit
Immunogen A synthesized peptide derived from human UBE2U(Accession Q5VVX9), corresponding to amino acid residues K135-R185.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 148581
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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