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Invitrogen™ UBE3C Polyclonal Antibody
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Catalog No. PIPA5110540
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100 μL
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PIPA5110540 100 μL
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Catalog No. PIPA5110540 Supplier Invitrogen™ Supplier No. PA5110540
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PISLEDLKSF TNYSGGYSAD HPVIKVFWRV VEGFTDEEKR KLLKFVTSCS RPPLLGFKEL YPAFCIHNGG SDLERLPTAS TCMNLLKLPE FYDETLLRSK LLYAIECAAG FELS Product note: Prior to December 2023, PA5-110540 was manufactured using a Recombinant fusion protein immunogen containing a sequence corresponding to amino acids 1-270 of human UBE3C. The affected lots are: WE3272737, WL3440149, XG3626363, 334B8A30, WH3338145, and VE2999302. Beginning in January 2024, all lots have been produced using a Recombinant fusion protein immunogen containing a sequence corresponding to amino acids 970-1083 of human UBE3C. Refer to the datasheets linked below for lot-specific immunogen information.

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE3C
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.81 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene UBE3C
Gene Accession No. Q15386
Gene Alias AI853514; HectH2; HECT-type ubiquitin transferase E3C; KIAA0010; KIAA10; mKIAA0010; RGD1559986; Ube3c; ubiquitin protein ligase E3C; ubiquitin-protein isopeptide ligase (E3); ubiquitin-protein ligase E3C
Gene Symbols UBE3C
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 970-1083 of human UBE3C (NP_0554862).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9690
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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