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Invitrogen™ UBE3C Polyclonal Antibody

Catalog No. PIPA531350
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100 μL
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PIPA531350 100 μL
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Catalog No. PIPA531350 Supplier Invitrogen™ Supplier No. PA531350

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, HepG2, HCT116, mouse brain. Predicted reactivity: Mouse (88%), Chicken (87%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE3C
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene UBE3C
Gene Accession No. Q15386, Q80U95
Gene Alias AI853514; HectH2; HECT-type ubiquitin transferase E3C; KIAA0010; KIAA10; mKIAA0010; RGD1559986; Ube3c; ubiquitin protein ligase E3C; ubiquitin-protein isopeptide ligase (E3); ubiquitin-protein ligase E3C
Gene Symbols UBE3C
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human UBE3C. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100763, 9690
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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