Invitrogen™ UBE3C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531350

Catalog No. PIPA531350

Description

Recommended positive controls: HeLa, HepG2, HCT116, mouse brain. Predicted reactivity: Mouse (88%), Chicken (87%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Specifications

• Antigen: UBE3C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBE3C
• Gene Alias: AI853514; HectH2; HECT-type ubiquitin transferase E3C; KIAA0010; KIAA10; mKIAA0010; RGD1559986; Ube3c; ubiquitin protein ligase E3C; ubiquitin-protein isopeptide ligase (E3); ubiquitin-protein ligase E3C
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100763, 9690
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q15386, Q80U95
• Gene Symbols: UBE3C
• Immunogen: Recombinant fragment corresponding to a region within amino acids 114 and 387 of Human UBE3C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov