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Invitrogen™ UBE4A Polyclonal Antibody
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Catalog No. PIPA5120865
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PIPA5120865 100 μL
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Catalog No. PIPA5120865 Supplier Invitrogen™ Supplier No. PA5120865
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Description

Rabbit Polyclonal Antibody

Positive test controls include: MCF7, HepG2, 293T, Mouse kidney, Mouse pancreas, Mouse liver. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: FLLDEAIQYL SKIKIQQIEK DRGEWDSLTP EARREKEAGL QMFGQLARFH NIMSNETIGT LAFLTSEIKS LFVHPFLAER IISMLNYFLQ HLVGPKMGAL KVKDFSEFDF KPQQLVSDIC TIYLNLGDEE NFCATVPKDG RSYSPTLFAQ TVRVLKKINK PGNMIMAFSN LAERIKSLAD LQQQEEETYA DACDEFLDPI MSTLMCDPVV LPSSRVTVDR STIARHLLSD QTDPFNRSPL TMDQIRPNTE LKEKIQRWLA ERKQQKEQLE.

Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE4A
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.75 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ube4a
Gene Accession No. E9Q735, Q14139, Q6P7A2
Gene Alias 4732444G18Rik; 9930123J21Rik; Ab2-232; E4; KIAA0126; RING-type E3 ubiquitin transferase E4 A; UBE4A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; UBOX2; UFD2; UFD2b
Gene Symbols Ube4a
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140630, 315608, 9354
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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