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Invitrogen™ UBE4A Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5120865
Description
Positive test controls include: MCF7, HepG2, 293T, Mouse kidney, Mouse pancreas, Mouse liver. The target is usually found in the following locations: Cytoplasm. Immunogen sequence: FLLDEAIQYL SKIKIQQIEK DRGEWDSLTP EARREKEAGL QMFGQLARFH NIMSNETIGT LAFLTSEIKS LFVHPFLAER IISMLNYFLQ HLVGPKMGAL KVKDFSEFDF KPQQLVSDIC TIYLNLGDEE NFCATVPKDG RSYSPTLFAQ TVRVLKKINK PGNMIMAFSN LAERIKSLAD LQQQEEETYA DACDEFLDPI MSTLMCDPVV LPSSRVTVDR STIARHLLSD QTDPFNRSPL TMDQIRPNTE LKEKIQRWLA ERKQQKEQLE.
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
Specifications
UBE4A | |
Polyclonal | |
Unconjugated | |
Ube4a | |
4732444G18Rik; 9930123J21Rik; Ab2-232; E4; KIAA0126; RING-type E3 ubiquitin transferase E4 A; UBE4A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; UBOX2; UFD2; UFD2b | |
Rabbit | |
Affinity Chromatography | |
RUO | |
140630, 315608, 9354 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot | |
0.75 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
E9Q735, Q14139, Q6P7A2 | |
Ube4a | |
Recombinant fusion protein containing a sequence corresponding to amino acids 797-1066 of human UBE4A (NP_001191006.1). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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