Invitrogen™ UBE4B Recombinant Rabbit Monoclonal Antibody (JE55-76)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA542492

Catalog No. PIMA542492

Description

Positive Control: HepG2 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, rat skeletal muscle tissue, human lung carcinoma tissue, N2A whole cell lysate. Subcellular Location: Nucleus, Cytoplasm.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.

Specifications

• Antigen: UBE4B
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: O95155, Q9ES00
• Gene Symbols: UBE4B
• Immunogen: Synthetic peptide within N-terminal Human UBE4B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: JE55-76
• Conjugate: Unconjugated
• Gene: UBE4B
• Gene Alias: 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; E4; HDNB1; homologous to yeast UFD2; homozygously deleted in neuroblastoma 1; homozygously deleted in neuroblastoma-1; KIAA0684; mKIAA0684; RING-type E3 ubiquitin transferase E4 B; Ube4b; Ubiquitin conjugation factor E4 B; ubiquitin fusion degradation protein 2; ubiquitination factor E4B; ubiquitination factor E4B (homologous to yeast UFD2); ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitination factor E4B, UFD2 homolog; ubiquitin-fusion degradation protein 2; UBOX3; UFD2; Ufd2a; UFD2A-III/UBE4B-III splice isoform; Ufd2p
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10277, 298652, 63958
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid