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Invitrogen™ UBE4B Recombinant Rabbit Monoclonal Antibody (JE55-76)
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Catalog No. PIMA542492
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100 μL
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PIMA542492 100 μL
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Catalog No. PIMA542492 Supplier Invitrogen™ Supplier No. MA542492
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: HepG2 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, rat skeletal muscle tissue, human lung carcinoma tissue, N2A whole cell lysate. Subcellular Location: Nucleus, Cytoplasm.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B represents an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. UBE4B also the strongest candidate among the neuroblastoma tumor suppressors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBE4B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE55-76
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene UBE4B
Gene Accession No. O95155, Q9ES00
Gene Alias 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; E4; HDNB1; homologous to yeast UFD2; homozygously deleted in neuroblastoma 1; homozygously deleted in neuroblastoma-1; KIAA0684; mKIAA0684; RING-type E3 ubiquitin transferase E4 B; Ube4b; Ubiquitin conjugation factor E4 B; ubiquitin fusion degradation protein 2; ubiquitination factor E4B; ubiquitination factor E4B (homologous to yeast UFD2); ubiquitination factor E4B (UFD2 homolog, yeast); ubiquitination factor E4B, UFD2 homolog; ubiquitin-fusion degradation protein 2; UBOX3; UFD2; Ufd2a; UFD2A-III/UBE4B-III splice isoform; Ufd2p
Gene Symbols UBE4B
Host Species Rabbit
Immunogen Synthetic peptide within N-terminal Human UBE4B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10277, 298652, 63958
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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