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Invitrogen™ UBF-1 Polyclonal Antibody
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Catalog No. PIPA536153
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100 μL
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PIPA536153 100 μL
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Catalog No. PIPA536153 Supplier Invitrogen™ Supplier No. PA536153
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 90 kDa. Purity is >95% by SDS-PAGE.

UBF-1 encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBF-1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene UBTF
Gene Accession No. P17480, P25976, P25977
Gene Alias 90-kDa nucleolus organizer region autoantigen; A930005G04Rik; Autoantigen NOR-90; NOR90; NOR-90; Nucleolar transcription factor 1; Tcfubf; transcription factor UBF; UBF; UBF1; UBF-1; UBF2; Ubtf; upstream binding transcription factor, RNA polymerase I; upstream-binding factor 1
Gene Symbols UBTF
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 500-550 of human UBF-1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21429, 25574, 7343
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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