UBF-1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA578213

Catalog No. PIPA578213

Description

Positive Control: HepG2 nuclear extract Predicted Reactivity: Mouse (100%), Rat (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

UBF-1 encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Specifications

• Antigen: UBF-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBTF
• Gene Alias: 90-kDa nucleolus organizer region autoantigen; A930005G04Rik; Autoantigen NOR-90; NOR90; NOR-90; Nucleolar transcription factor 1; Tcfubf; transcription factor UBF; UBF; UBF1; UBF-1; UBF2; Ubtf; upstream binding transcription factor, RNA polymerase I; upstream-binding factor 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7343
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P17480
• Gene Symbols: UBTF
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human UBTF. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov