Invitrogen™ UBF-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536153

Catalog No. PIPA536153

Description

This antibody detects endogenous protein at a molecular weight of 90 kDa. Purity is >95% by SDS-PAGE.

UBF-1 encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

Specifications

• Antigen: UBF-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBTF
• Gene Alias: 90-kDa nucleolus organizer region autoantigen; A930005G04Rik; Autoantigen NOR-90; NOR90; NOR-90; Nucleolar transcription factor 1; Tcfubf; transcription factor UBF; UBF; UBF1; UBF-1; UBF2; Ubtf; upstream binding transcription factor, RNA polymerase I; upstream-binding factor 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21429, 25574, 7343
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P17480, P25976, P25977
• Gene Symbols: UBTF
• Immunogen: Synthetic peptide corresponding to amino acids 500-550 of human UBF-1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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