Invitrogen™ Ubinuclein 1 Monoclonal Antibody (UBN1-02)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA110458

Catalog No. PIMA110458

Description

This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.

Specifications

• Antigen: Ubinuclein 1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: Q9NPG3
• Gene Symbols: UBN1
• Immunogen: Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunoprecipitation, Western Blot
• Clone: UBN1-02
• Conjugate: Unconjugated
• Gene: UBN1
• Gene Alias: 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 29855
• Content And Storage: 4°C, do not freeze
• Form: Liquid