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Invitrogen™ Ubinuclein 1 Monoclonal Antibody (UBN1-02)
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Catalog No. PIMA110458
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100 μg
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PIMA110458 100 μg
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Catalog No. PIMA110458 Supplier Invitrogen™ Supplier No. MA110458
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Description

Mouse Monoclonal Antibody

This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.
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Specifications

Antigen Ubinuclein 1
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone UBN1-02
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene UBN1
Gene Accession No. Q9NPG3
Gene Alias 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
Gene Symbols UBN1
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29855
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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