Invitrogen™ Ubinuclein 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103360

Catalog No. PIPA5103360

Description

Antibody detects endogenous levels of total Ubinuclein.

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.

Specifications

• Antigen: Ubinuclein 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBN1
• Gene Alias: 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170644, 29855
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q4G0F8, Q9NPG3
• Gene Symbols: UBN1
• Immunogen: A synthesized peptide derived from human UBN1(Accession Q9NPG3), corresponding to amino acid residues Q303-L353.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov