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Invitrogen™ Ubiquilin 1 Polyclonal Antibody
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Catalog No. PIPA522174
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100 μL
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PIPA522174 100 μL
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Catalog No. PIPA522174 Supplier Invitrogen™ Supplier No. PA522174
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Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (90%), Rat (90%), Sheep (96%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PLIC1 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and is found in lesions associated with Alzheimer's and Parkinson's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ubiquilin 1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Ubqln1
Gene Accession No. Q8R317, Q9UMX0
Gene Alias 1110046H03Rik; 1810030E05Rik; AU019746; C77538; D13Ertd372e; Da41; Dsk2; hPLIC-1; I79_020705; Plic1; PLIC-1; Protein linking IAP with cytoskeleton 1; testicular tissue protein Li 219; ubiquilin 1; ubiquilin-1; UBQLN1; UBQN; XDRP1
Gene Symbols Ubqln1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Ubiquilin 1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29979, 56085
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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