Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA585270

Invitrogen™ Ubiquitin B Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA585270
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA585270 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA585270 Supplier Invitrogen™ Supplier No. PA585270
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (99%), Xenopus laevis (99%), Pig (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%). Positive Control: Target recombinant protein. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Ubiquitin is a highly conserved protein of about 8.5 kDa molecular weight, which has an ATP dependent role in the targeting of proteins for proteolytic degradation. To perform this function, the protein to be degraded is first covalently attached to the C terminus of ubiquitin, and the ubiquitinated complex is then recognized by a complex of degradative enzymes. Interestingly, ubiquitin also becomes covalently bonded to many types of pathological inclusions, which appear to be resistant to normal degradation. Therefore, ubiquitin antibodies are very useful for studies of these inclusions. For example, the neurofibrillary tangles and paired helical filaments diagnostic of Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease are all heavily ubiquitinated and can be readily visualized with ubiquitin antibodies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ubiquitin B
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Concentration 0.82 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene UBB
Gene Accession No. P0CG47
Gene Alias AL033289; epididymis secretory protein Li 50; HEL-S-50; HUBCEP52; im:6892314; im:6892314 protein; MGC127041; polyubiquitin; polyubiquitin B; polyubiquitin-B; RPL40; Rps27a; si:ch211-202a12.3; Uba52; Ubb; Ubb2; UBC; Ubi-p63E; Ubiquitin; ubiquitin B; ubiquitin C; Ubiquitin-related; zgc:172187; zUBC
Gene Symbols UBB
Host Species Rabbit
Immunogen Full length human Ubiquitin B Recombinant protein.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7314
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.