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Tocris Bioscience™ UBP 310
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Catalog No. 362150R
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Catalog No. Quantity
36-215-0R 50 mg
36-211-0R 10 mg
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Catalog No. 36-215-0R Supplier Tocris Bioscience™ Supplier No. 3621/50
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Description

GluK1-selective kainate antagonist

UBP 310 is a GluK1 (formerly GLUK5) kainate receptor antagonist (IC50 = 130 nM); also blocks recombinant homomeric GluK3 (forrmerly GLUK7) receptors. Displays 12,700-fold selectivity for GluK1 (formerly GLUK5) over GluK2 (formerly GLUK6). Exhibits no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. Apparent KD value is 18 ± 4 nM for depression of kainate responses on the dorsal root.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Quantity 50 mg
Product Type UBP 310
Purity >98%
Molecular Weight (g/mol) 353.35
Inhibitors UBP 310

For Research Use Only

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