Invitrogen™ UBR2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542309

Catalog No. PIPA542309

Description

Peptide sequence: GLKLLSWLGS IIGYSDGLRR ILCQVGLQEG PDGENSSLVD RLMLSDSKLW Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 91%.

The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.

Specifications

• Antigen: UBR2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBR2
• Gene Alias: 9930021A08Rik; AI462103; AW540746; bA49A4.1; C6orf133; dJ242G1.1; dJ392M17.3; E130209G04Rik; E3 ubiquitin-protein ligase UBR2; Kiaa0349; mKIAA0349; N-recognin-2; RING-type E3 ubiquitin transferase UBR2; si:ch211-239i4.2; ubiquitin ligase E3 alpha-II; ubiquitin protein ligase E3 component n-recognin 2; ubiquitin-protein ligase E3-alpha-2; Ubiquitin-protein ligase E3-alpha-II; Ubr2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23304
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8IWV8
• Gene Symbols: UBR2
• Immunogen: Synthetic peptide directed towards the C-terminal of human UBR2 (aa 314-363).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG