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Invitrogen™ UBR4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5116101
Description
Antibody detects endogenous levels of total UBR4.
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.
Specifications
UBR4 | |
Polyclonal | |
Unconjugated | |
UBR4 | |
1810009A16Rik; 600 kDa retinoblastoma protein-associated factor; A930005E13Rik; D930005K06Rik; E3 ubiquitin-protein ligase UBR4; Gm1032; Gm1666; KIAA0462; KIAA1307; mKIAA0462; N28143; N-recognin-4; p600; Rbaf600; retinoblastoma-associated factor 600; retinoblastoma-associated factor 600-like protein; retinoblastoma-associated factor of 600 kDa; RING-type E3 ubiquitin transferase UBR4; ubiquitin protein ligase E3 component n-recognin 4; UBR4; Zinc finger UBR1-type protein 1; zinc finger, UBR1 type 1; ZUBR1 | |
Rabbit | |
Affinity Chromatography | |
RUO | |
23352, 313658, 69116 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide | |
A2AN08, Q2TL32, Q5T4S7 | |
UBR4 | |
A synthesized peptide derived from human UBR4(Accession Q5T4S7), corresponding to amino acid residues P4006-A4056. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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