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Invitrogen™ UBR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116101

Catalog No. PIPA5116101


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Description

Description

Antibody detects endogenous levels of total UBR4.

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

UBR4
Polyclonal
Unconjugated
UBR4
1810009A16Rik; 600 kDa retinoblastoma protein-associated factor; A930005E13Rik; D930005K06Rik; E3 ubiquitin-protein ligase UBR4; Gm1032; Gm1666; KIAA0462; KIAA1307; mKIAA0462; N28143; N-recognin-4; p600; Rbaf600; retinoblastoma-associated factor 600; retinoblastoma-associated factor 600-like protein; retinoblastoma-associated factor of 600 kDa; RING-type E3 ubiquitin transferase UBR4; ubiquitin protein ligase E3 component n-recognin 4; UBR4; Zinc finger UBR1-type protein 1; zinc finger, UBR1 type 1; ZUBR1
Rabbit
Affinity Chromatography
RUO
23352, 313658, 69116
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide
A2AN08, Q2TL32, Q5T4S7
UBR4
A synthesized peptide derived from human UBR4(Accession Q5T4S7), corresponding to amino acid residues P4006-A4056.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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