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Invitrogen™ UBXN2B Polyclonal Antibody
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Catalog No. PIPA560969
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100 μL
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PIPA560969 100 μL
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Catalog No. PIPA560969 Supplier Invitrogen™ Supplier No. PA560969
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GEQERRSSGP RPPSARDLQL ALAELYEDEV KCKSSKSNRP KATVFKSPRT PPQRFYSSEH EYSGLNIVRP S Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 75%.

UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UBXN2B
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene UBXN2B
Gene Accession No. Q14CS0
Gene Alias NSFL1 cofactor p37; p37; p97 cofactor p37; UBX domain protein 2B; UBX domain-containing protein 2B; UBXN2B
Gene Symbols UBXN2B
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human UBXN2B. Recombinant protein control fragment (Product #RP-100343).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 137886
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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