Invitrogen™ UBXN2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560969

Catalog No. PIPA560969

Description

Immunogen sequence: GEQERRSSGP RPPSARDLQL ALAELYEDEV KCKSSKSNRP KATVFKSPRT PPQRFYSSEH EYSGLNIVRP S Highest antigen sequence identity to the following orthologs: Mouse - 69%, Rat - 75%.

UBXD2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein that contains one UBX domain and one SEP domain. UBXN2B is required for ER and Golgi biogenesis and also plays a role in their maintenance during interphase, as well as their reassembly at the end of mitosis. Through interaction with VCP, UBXN2B forms a complex that has membrane fusion activity. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity.

Specifications

• Antigen: UBXN2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBXN2B
• Gene Alias: NSFL1 cofactor p37; p37; p97 cofactor p37; UBX domain protein 2B; UBX domain-containing protein 2B; UBXN2B
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 137886
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q14CS0
• Gene Symbols: UBXN2B
• Immunogen: Recombinant protein corresponding to Human UBXN2B. Recombinant protein control fragment (Product #RP-100343).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG