Invitrogen™ UBXN6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA584520

Catalog No. PIPA584520

Description

Immunogen sequence: KFFQEFKADI KFKSAGPGQK LKESVGEKAH KEKPNQPAPR PPRQGPTNEA QMAAAAALAR LEQKQSRA.

May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes (PubMed:26475856). As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation (PubMed:21822278, PubMed:23335559). It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:19275885). Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes (PubMed:27753622). [UniProt].

Specifications

• Antigen: UBXN6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UBXN6
• Gene Alias: 1200008L11Rik; 2210415J11Rik; AU040909; CTB-50L17.16; UBX domain containing 1; UBX domain protein 6; UBX domain-containing 1; UBX domain-containing 2; UBX domain-containing protein 1; UBX domain-containing protein 6; UBXD1; Ubxdc2; Ubxn6
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80700
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BZV1
• Gene Symbols: UBXN6
• Immunogen: Recombinant protein corresponding to Human UBXN6. Recombinant protein control fragment (Product #RP-105214).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG