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UCH-L1/PGP9.5 Antibody (rUCHL1/775) - Azide and BSA Free, Novus Biologicals™
SDP

Catalog No. NBP275775 Shop All R&D Systems Products
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NBP275775 100 μg
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Catalog No. NBP275775 Supplier Novus Biologicals Supplier No. NBP275775
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Description

Mouse Monoclonal Antibody

UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human, Rat samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.

Specifications

Antigen UCH-L1/PGP9.5
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone rUCHL1/775
Concentration 0.2 mg/ml
Conjugate Unconjugated
Dilution Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Formulation 10 mM PBS with No Preservative
Gene Accession No. P09936
Gene Alias EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Gene Symbols UCHL1
Host Species Mouse
Immunogen Recombinant full-length human UCH-L1/PGP9.5 protein (Uniprot: P09936)
Purification Method Protein A or G purified
Quantity 100 μg
Primary or Secondary Primary
Gene ID (Entrez) 7345.0
Test Specificity This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Target Species Human, Rat
Content And Storage Store at 4°C.
Form Purified
Isotype IgG1 κ
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