UCH-L1/PGP9.5 Antibody (UCHL1/841), Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP24479600	Novus Biologicals NBP2447960.02MG	0.02 mg
NBP24479601	Novus Biologicals NBP2447960.1MG	0.1 mg
NBP24479602	Novus Biologicals NBP2447960.2MG	0.2 mg

Description

Ensure accurate, reproducible results in Western Blot, Immunofluorescence

UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human samples. It is validated for Western Blot.

Specifications

• Antigen: UCH-L1/PGP9.5
• Concentration: 0.2 mg/mL
• Applications: Western Blot, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Mouse
• Research Discipline: Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene ID (Entrez): 7345
• Immunogen: Recombinant human UCHL1 protein
• Primary or Secondary: Primary
• Content And Storage: Store at 4C.

• Clone: UCHL1/841
• Dilution: Western Blot 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
• Classification: Monoclonal
• Form: Purified
• Regulatory Status: RUO
• Target Species: Human
• Gene Alias: EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
• Gene Symbols: UCHL1
• Isotype: IgG2a κ
• Purification Method: Protein A or G purified
• Test Specificity: This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

For Research Use Only