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Invitrogen™ UCMA Polyclonal Antibody
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Catalog No. PIPA561295
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100 μL
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PIPA561295 100 μL
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Catalog No. PIPA561295 Supplier Invitrogen™ Supplier No. PA561295
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YYEEQRNEFE NFVEEQNDEQ EERSREAVEQ WRQWHYDGLH PSYLYNRHHT Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 88%.

UCMA is a gene that encodes for a protein that is specific to chondrocytes and highly charged. This protein is expressed abundantly in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the protein has been associated with osteoarthritis in humans. Alternative splicing of the gene results in multiple transcript variants that encode different isoforms. UCMA is also associated with diseases such as Osteoarthritis and Poland Syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UCMA
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene UCMA
Gene Accession No. Q8WVF2
Gene Alias 1110017I16Rik; AW121955; C10orf49; Gla-rich protein; GRP; GRP/UCMA; RGD1308977; Ucma; ucma {ECO:0000250; Ucma-C; UniProtKB:Q14BU0}; Unique cartilage matrix-associated protein; unique cartilage matrix-associated protein {ECO:0000250; Unique cartilage matrix-associated protein C-terminal fragment; upper zone of growth plate and cartilage matrix associated; upper zone of growth plate and cartilage matrix associated protein
Gene Symbols UCMA
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human UCMA. Recombinant protein control fragment (Product #RP-100763).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 221044
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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