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UCP-1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984299
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100 μL
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50-198-4299 100 μL
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Catalog No. 50-198-4299 Supplier Bioss Supplier No. BS1925R
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Rabbit Polyclonal Antibody

Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Specifications

Antigen UCP-1
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Ucp1
Gene Accession No. P25874
Gene Alias AI385626; HGNC:12517; Mitochondrial brown fat uncoupling protein 1; SLC25A7; Solute carrier family 25 member 7; Thermogenin; UCP; UCP 1; Ucp1; Ucpa; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp
Gene Symbols Ucp1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human UCP-1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7350
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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