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Invitrogen™ UCP1 Recombinant Rabbit Monoclonal Antibody (0B3K2)
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Catalog No. FEMA551239
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100 μL
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FEMA551239 100 μL
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Catalog No. FEMA551239 Supplier Invitrogen™ Supplier No. MA551239
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: QEFLTAGKET APSLGSKILA GLTTGGVAVF IGQPTEVVKV RLQAQSHLHG IKPRYTGTYN AYRIIATTEG LTGLWKGTTP NLMRSVIINC TELVTYDLMK E.

Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UCP1
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 0B3K2
Concentration 0.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Ucp1
Gene Accession No. P12242
Gene Alias AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product
Gene Symbols Ucp1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100-200 of human UCP1 (NP_068605.1).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22227
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Format Liquid
Isotype IgG
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