Invitrogen™ UCP1 Recombinant Rabbit Monoclonal Antibody (0B3K2)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA551239

Catalog No. FEMA551239

Description

Immunogen sequence: QEFLTAGKET APSLGSKILA GLTTGGVAVF IGQPTEVVKV RLQAQSHLHG IKPRYTGTYN AYRIIATTEG LTGLWKGTTP NLMRSVIINC TELVTYDLMK E.

Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Specifications

• Antigen: UCP1
• Classification: Recombinant Monoclonal
• Concentration: 0.67 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P12242
• Gene Symbols: Ucp1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human UCP1 (NP_068605.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Format: Liquid

• Applications: ELISA, Western Blot
• Clone: 0B3K2
• Conjugate: Unconjugated
• Gene: Ucp1
• Gene Alias: AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22227
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid
• Isotype: IgG