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Invitrogen™ UCP1 Recombinant Rabbit Monoclonal Antibody (1H17L25)

Catalog No. 703793
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70-379-3 100 μg
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Catalog No. 70-379-3 Supplier Invitrogen™ Supplier No. 703793
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Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Human and Bovine.

Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UCP1
Applications Western Blot
Classification Recombinant Monoclonal
Clone 1H17L25
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Ucp1
Gene Accession No. P04633, P12242, P25874
Gene Alias AI385626; HGNC:12517; mitochondrial brown fat uncoupling protein 1; SLC25A7; solute carrier family 25 member 7; Thermogenin; Ucp; UCP 1; Ucp1; Ucpa; uncoupling protein; uncoupling protein 1; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial; Uncp; unnamed protein product
Gene Symbols Ucp1
Host Species Rabbit
Immunogen Peptides corresponding to human UCP1 [1)aa295-aa304 2) aa149-aa158].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22227, 24860, 7350
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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