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UCP2 Mouse anti-Human, Clone:3F1B9, Abnova™

Catalog No. 89333611 Shop All Abnova Corporation Products
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89-333-611 100 μg
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Catalog No. 89-333-611 Supplier Abnova Corporation Supplier No. MAB17188
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Description

Mouse monoclonal antibody raised against recombinant human UCP2.

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5′-UCP3-UCP2-3′. [provided by RefSeq]

Specifications

Antigen UCP2
Applications ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 3F1B9
Conjugate Unconjugated
Description uncoupling protein 2 (mitochondrial, proton carrier)
Dilution ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry
Immunocytochemistry (1:200-1:1000)
Flow Cytometry (1:200-1:400)
The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene UCP2
Gene Alias BMIQ4, SLC25A8, UCPH
Host Species Mouse
Immunogen Recombinant protein corresponding to amino acid 1-309 of human UCP2 from E. coli.
Quantity 100 μg
Gene ID (Entrez) 7351
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG2a
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