Invitrogen™ UCP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120884

Catalog No. PIPA5120884

Description

Positive test controls include: Raji, A-549, HT-29, RAW264.7, Mouse heart, Rat heart. The target is usually found in the following locations: Mitochondrion inner membrane, Multi-pass membrane protein. Immunogen sequence: EHASIGSRLL AGSTTGALAV AVAQPTDVVK VRFQAQARAG GGRRYQSTVN AYKTIAREEG FRGLWKGTSP NVARNAIVNC AELVTYDLIK DALLKANLMT.

UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP2 gene is expressed in many tissues, with the greatest expression in skeletal muscle. UCP2 is thought to play a role in non shivering thermogenesis, obesity and diabetes.

Specifications

• Antigen: UCP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Ucp2
• Gene Alias: BMIQ4; Mitochondrial uncoupling protein 2; Slc25a8; Solute carrier family 25 member 8; UCP 2; Ucp2; UCPH; uncoupling protein; uncoupling protein 2; uncoupling protein 2 (mitochondrial, proton carrier); uncoupling protein 2, mitochondrial
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22228, 54315, 7351
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P55851, P56500, P70406
• Gene Symbols: Ucp2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 112-211 of human UCP2 (NP_003346.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG