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Invitrogen™ UCP4 Polyclonal Antibody
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Catalog No. PIPA5116568
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100 μL
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PIPA5116568 100 μL
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Catalog No. PIPA5116568 Supplier Invitrogen™ Supplier No. PA5116568
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Description

Rabbit Polyclonal Antibody

Positive Samples: mouse brain, rat brain Immunogen sequence: NQPRDKQGRG LLYKSSTD.

UCP4 is a 323 amino acid mitochondrial uncoupling protein belonging to the large mitochondrial substrate carrier family with three Solcar repeats. UCP4 is a mitochondrial transport carrier that facilitates the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. It reduces the mitochondrial membrane potential in mammalian cells and is involved in thermoregulatory heat production. UCP4 creates proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis resulting in dissipation of energy in the form of heat. UCP4 is usually found in adult and fetal brain, with low levels in spinal chord, corpus callosum and substantia nigra.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UCP4
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 4.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SLC25A27
Gene Accession No. O95847
Gene Alias 3632410G24Rik; 9430092A03Rik; D530043E16Rik; Mitochondrial uncoupling protein 4; slc25a27; Solute carrier family 25 member 27; solute carrier family 25, member 27; UCP 4; ucp4; uncoupling protein; uncoupling protein 4; uncoupling protein UCP-4; UNQ772/PRO1566; zgc:63899
Gene Symbols SLC25A27
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 201-300 of human SLC25A27 (NP_0042683).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 74011, 85262, 9481
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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