Invitrogen™ UGDH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588347

Catalog No. PIPA588347

Description

Immunogen sequence: EGTAIKDLKN PDRVLIGGDE TPEGQRAVQA LCAVYEHWVP REKILTTNTW SSELSKLAAN AFLAQRISSI NSISALCEAT GADVEEVATA IGMDQRIGNK FLKASVGFGG SCFQKDVLNL VYLCEALNLP EVARYWQQVI DMNDYQRRRF ASRIIDSLFN TVTDKKIAIL GFAFKKDTGD TRESSSIYIS KYLMDEGAHL HIYDPKVPRE QIVVDLSHPG VSEDDQVSRL VTISKDPYEA CDGAHAVVIC TEWDMFKELD YERIHKKMLK PAFIFDGRRV LDGLHNELQT IGFQIETIGK KVSSKRIPYA PSGEIPKFSL QDPPNKKPKV; Positive Samples: HeLa, THP-1, 22Rv1, ES-2, U-937, Mouse kidney, Mouse intestine.

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.

Specifications

• Antigen: UGDH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UGDH
• Gene Alias: GDH; UDP UGD; UDPGDH; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-glucose dehydrogeanse; UDP-glucose dehydrogenase; UGD; UGDH; uridine diphospho-glucose dehydrogenase
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22235, 7358
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Western Blot
• Concentration: 0.44 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O60701, O70475
• Gene Symbols: UGDH
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 165-494 of human UGDH (NP_0033501).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG