Invitrogen™ UGDH Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557754

Catalog No. PIPA557754

Description

Immunogen sequence: IDMNDYQRRR FASRIIDSLF NTVTDKKIAI LGFAFKKDTG DTRESSSIYI SKYLMDEGAH LHIYDPKVPR EQIVVDLSHP GVSEDDQVSR LV Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.

The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.

Specifications

• Antigen: UGDH
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: UGDH
• Gene Alias: GDH; UDP UGD; UDPGDH; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDP-glucose dehydrogeanse; UDP-glucose dehydrogenase; UGD; UGDH; uridine diphospho-glucose dehydrogenase
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7358
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O60701
• Gene Symbols: UGDH
• Immunogen: Recombinant protein corresponding to Human UGDH. Recombinant protein control fragment (Product #RP-96633).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov