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Invitrogen™ UGT1A3 Polyclonal Antibody

Catalog No. PIPA5143912
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100 μg
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Catalog No. Quantity
PIPA5143912 100 μg
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Catalog No. PIPA5143912 Supplier Invitrogen™ Supplier No. PA5143912

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

UDP-glucuronosyltransferase 1-3 is an enzyme that in humans is encoded by the UGT1A3 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen UGT1A3
Applications ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene UGT1A3
Gene Accession No. P35503, Q64637
Gene Alias GNT1; polypeptide A3; UDP glucuronosyltransferase 1 family; UDP-glucuronosyltransferase 1A3; UGT1
Gene Symbols UGT1A3
Host Species Rabbit
Immunogen E.coli-derived human UGT1A3 recombinant protein (Position: H92-C128).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 396551, 54659
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG
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