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Invitrogen™ UGT1A4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5102796
Description
Antibody detects endogenous levels of total UGT1A4.
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.
Specifications
UGT1A4 | |
Polyclonal | |
Unconjugated | |
UGT1A4 | |
bilirubin UDP-glucuronosyltransferase isozyme 2; bilirubin-specific UDPGT isozyme 2; GNT1; hUG-BR2; UDP glucuronosyltransferase 1 family, polypeptide A4; UDP glucuronosyltransferase family 1 member A4; UDP glycosyltransferase 1 family, polypeptide A4; UDP-glucuronosyltransferase 1 family polypeptide A4s; UDP-glucuronosyltransferase 1-4; UDP-glucuronosyltransferase 1A4; UDP-glucuronosyltransferase 1-D; UDPGT; UDPGT 1-4; UGT1; UGT1.4; UGT1-04; UGT1A4; UGT1A4S; UGT1D; UGT-1D | |
Rabbit | |
Affinity chromatography | |
RUO | |
54657 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
P22310 | |
UGT1A4 | |
A synthesized peptide derived from human UGT1A4(Accession P22310), corresponding to amino acid residues A26-T76. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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